Activation of the integrins α5β1 and αvβ3 and focal adhesion kinase (FAK) during arteriogenesis
✍ Scribed by Wei-Jun Cai; Ming Bo Li; Xiaoqiong Wu; Song Wu; Wu Zhu; Dan Chen; Mingying Luo; Inka Eitenmüller; Andreas Kampmann; Jutta Schaper; Wolfgang Schaper
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 524 KB
- Volume
- 322
- Category
- Article
- ISSN
- 0300-8177
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Isoxazoline‐containing peptidomimetics, designed to be effective α~v~β~3~ and α~5~β~1~ integrin ligands, were synthesized through an original procedure involving __N__,__O__‐bis(trimethylsilyl)hydroxyamine conjugate addition to alkylidene acetoacetates, followed by intramolecular hemike
Bone sialoprotein (BSP), a secreted glycoprotein found in bone matrix, has been implicated in the formation of mammary microcalcifications and osteotropic metastasis of human breast cancer (HBC). BSP possesses an integrin-binding RGD (Arg-Gly-Asp) domain, which may promote interactions between HBC c
We have shown previously that switching of the ␣v-associated 1 and 5 integrin subunits during differentiation of myelin-forming oligodendrocytes may regulate important aspects of cell behaviour such as migration (Milner et al., 1996: J Neurosci 16:7240-7252). In this study we have examined the dev
CHO cells expressing a 5 b 1 integrin are more resistant to apoptosis and express more Bcl-2 than the same cells engineered to express a v b 1 or cytoplasmically truncated a 5 Dcb 1 integrin as their main fibronectin receptor. The Bcl-2 up-regulation by a 5 b 1 is mediated, at least in part, by the