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Activation of the Hippo pathway by CTLA-4 regulates the expression of Blimp-1 in the CD8 + T cell

✍ Scribed by Thaventhiran, James E.D. (author);Hoffmann, Anja (author);Magiera, Lukasz (author);De La Roche, Maike (author);Lingel, Holger (author);Brunner-Weinzierl, Monika (author);Fearon, Douglas T. (author)

Book ID: 118737929
Publisher: National Academy of Sciences
Year: 2012
Tongue: English
Weight: 80 KB
Volume: 109
Category: Article
ISSN: 0027-8424
DOI: 10.1073/pnas.1209115109

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## Abstract Regulatory T cells (Treg cells) have been well documented to have a crucial physiological role in preventing the development of autoimmune diseases and keeping self‐tolerance. Foxp3, a recently identified member of the forkhead transcription factors, serves as a master regulator for the