Activation of the fast transmembrane sodium current of single heart cells
β Scribed by Yu. I. Zil'berter; E. N. Timin
- Publisher
- Springer US
- Year
- 1982
- Tongue
- English
- Weight
- 203 KB
- Volume
- 94
- Category
- Article
- ISSN
- 0007-4888
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Single-channel currents from Na(+)-dependent K+ channels (KNa) were recorded from cell-attached and inside-out membrane patches of cultured avian trigeminal ganglion neurons by means of the patch-clamp technique. Single-channel properties, such as the high elementary conductance and the occurrence o
To record the fast Na+ current, spheroidal heart cells enzymatically-dispersed from 3 approximately 18-day-old chick embryos were used for voltage clamping. The peak of currents in response to voltage steps of 200 ms long from holding potentials of -90 approximately -105 mV were measured. The curren