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Activation of the Ca2+/calcineurin/NFAT2 pathway controls smooth muscle cell differentiation

✍ Scribed by Daniel Larrieu; Pierre Thiébaud; Cécile Duplàa; Igor Sibon; Nadine Thézé; Jean-Marie Daniel Lamazière

Book ID
118506236
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
719 KB
Volume
310
Category
Article
ISSN
0014-4827

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The calcineurin-mediated pathway is involved in skeletal and cardiac hypertrophy and vascular development in vivo, but the relationship between this pathway and the phenotype of smooth muscle cells (SMCs) remains unknown. Using visceral SMCs in culture as a model system of differentiated SMCs, we in