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Activation of the Akt/GSK3β signaling pathway mediates survival of vulnerable hippocampal neurons after transient global cerebral ischemia in rats

✍ Scribed by Endo, Hidenori; Nito, Chikako; Kamada, Hiroshi; Nishi, Tatsuro; Chan, Pak H

Book ID: 110046672
Publisher: Nature Publishing Group
Year: 2006
Tongue: English
Weight: 379 KB
Volume: 26
Category: Article
ISSN: 0271-678X
DOI: 10.1038/sj.jcbfm.9600303

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## Abstract Delayed neuronal cell death occurs in the vulnerable CA1 subfield of the hippocampus after transient global ischemia (TGI). We demonstrated previously, based on an experimental model of TGI, that the significantly increased content of oxidized proteins in hippocampal CA1 neuron was obse