Activation of T-cell receptor signaling in peripheral T-cell lymphoma cells plays an important role in the development of lymphoma-associated hemophagocytosis
✍ Scribed by Jun An; Hiroshi Fujiwara; Koichiro Suemori; Toshiyuki Niiya; Taichi Azuma; Kazushi Tanimoto; Toshiki Ochi; Yoshiki Akatsuka; Junichi Mineno; Hidetoshi Ozawa; Fumihiko Ishikawa; Kiyotaka Kuzushima; Masaki Yasukawa
- Publisher
- Carden Jennings Publishing
- Year
- 2011
- Tongue
- English
- Weight
- 572 KB
- Volume
- 93
- Category
- Article
- ISSN
- 0925-5710
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
he specificity of T-cell recognition events is essential for protective immune responses and in order to avoid autoimmunity. Binding of the T-cell receptor (TCR) to peptide bound to major histocompatibility complex (MHC) molecules is an early step for specific T-cell activation. This engagement lead
## Abstract HTLV‐I‐associated adult T‐cell leukemia/lymphoma (ATL) and human T‐cell lymphotropic virus type I (HTLV‐I)‐negative peripheral T‐cell lymphomas carry poor prognosis mainly because of acquired resistance to chemotherapy. We have shown that this disease is responsive to the combination of