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Activation of RyR Clusters during a Calcium Spark in Cardiac Myocytes

✍ Scribed by Brochet, Didier X.P.; Lederer, W. Jonathan


Book ID
122307530
Publisher
Biophysical Society
Year
2013
Tongue
English
Weight
43 KB
Volume
104
Category
Article
ISSN
0006-3495

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Calcium plays an essential role in excitation-contraction coupling in muscle, and derangements in calcium handling can produce a variety of potentially harmful conditions, especially in cardiac muscle. In cardiac tissue specialized invaginations of the sarcolemma, called T-tubules, penetrate deep in