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Activation of Rac-1 and Cdc42 stabilizes the microvascular endothelial barrier

✍ Scribed by Jens Waschke; Sabrina Burger; Fitz-Roy E. Curry; Detlev Drenckhahn; Roger H. Adamson


Book ID
106099731
Publisher
Springer
Year
2005
Tongue
English
Weight
406 KB
Volume
125
Category
Article
ISSN
1432-119X

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πŸ“œ SIMILAR VOLUMES


Role of Rac 1 and cAMP in endothelial ba
✍ Y. Baumer; V. Spindler; R.C. Werthmann; M. BΓΌnemann; J. Waschke πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 526 KB

## Abstract Barrier stabilizing effects of cAMP as well as of the small GTPase Rac 1 are well established. Moreover, it is generally believed that permeability‐increasing mediators such as thrombin disrupt endothelial barrier functions primarily via activation of Rho A. In this study, we provide ev