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Activation of protein kinases A and C increase lymphocyte penetration through endothelial monolayers

✍ Scribed by Risto Renkonen


Book ID
115923157
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
416 KB
Volume
267
Category
Article
ISSN
0014-5793

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We determined whether activation of phosphatidylinositol-specific phospholipase C (PI-PLC) and a subsequent increase in cytosolic calcium concentration ([Ca2+]i) was an obligatory signaling event mediating the increase in transendothelial permeability induced by bradykinin (BK) and alpha-thrombin (a