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Activation of protein kinase D (PKD) by signaling through Rho and the alpha subunit of the heterotrimeric G protein G13

โœ Scribed by Yuan, Jingzhen; Slice, Lee; Rozengurt, Enrique


Book ID
124131282
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
190 KB
Volume
120
Category
Article
ISSN
0016-5085

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## Abstract Mechanical stresses that are preferentially transmitted across the cell surface via transmembrane integrin receptors activate gene transcription by triggering production of intracellular chemical second messengers, such as cAMP. Here we show that the sensitivity of the cAMP signaling pa