Activation of protein kinase C enhances the infection of endothelial cells by human cytomegalovirus
✍ Scribed by Marlea E.P Slobbe-van Drunen; Renée C.R.M Vossen; Franka M.D Couwenberg; Martine M Hulsbosch; Johan W.M Heemskerk; Maria C.E van Dam-Mieras; Cathrien A Bruggeman
- Book ID
- 117366358
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 264 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0168-1702
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Studies were conducted to establish the relationship between deoxyguanosine kinase activity and human cytomegalovirus (HCMV) infection. Using both PAGE and isoelectric focusing techniques, extracts from untreated and infected cells were examined for deoxyguanosine kinase activity. The analyses resul
## Abstract The immediate‐early (IE) promoter of human cytomegalovirus (HCMV) constitutes a primary genetic switch, which determines the progression of viral infection. Earlier reports by others have shown mitogen‐activated protein kinase kinase kinase‐1 (MEKK1) to be able to up‐regulate HCMV‐IE pr