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Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain

✍ Scribed by Takanori Moriki; Hiroko Maruyama; Ichi N Maruyama


Book ID
115631261
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
403 KB
Volume
311
Category
Article
ISSN
0022-2836

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πŸ“œ SIMILAR VOLUMES


Molecular dynamics (MD) investigations o
✍ Pierre Aller; LoΓ―s Voiry; Norbert Garnier; Monique Genest πŸ“‚ Article πŸ“… 2005 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 555 KB

## Abstract The critical Val/Glu mutation in the membrane spanning domain of the rat Neu receptor confers the ability for ligand‐independent signaling and leads to increased dimerization and transforming ability. There is evidence that the two transmembrane interacting helices play a role in recept