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Activation of pp60c-src is necessary for human vascular smooth muscle cell migration

✍ Scribed by Leila Mureebe; Peter R Nelson; Shinji Yamamura; Joel Lawitts; K.Craig Kent


Book ID
117220783
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
820 KB
Volume
122
Category
Article
ISSN
0039-6060

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## Abstract Transforming growth factor‐β1 (TGF‐β1) stimulates expression of plasminogen activator inhibitor type‐1 (PAI‐1), a serine protease inhibitor (__SERPIN__) important in the control of stromal barrier proteolysis and cell‐to‐matrix adhesion. Pharmacologic agents that target MEK (PD98059, U0