Activation of phospholipase A2 in rabbit erythrocyte membranes by a novel hemolytic toxin (H-toxin) of Clostridium septicum
β Scribed by Sanae Takano; Masatoshi Noda; Iwao Kato
- Book ID
- 109316658
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 195 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0378-1097
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
C difficile toxin B i s a potent cytotoxin known to disrupt the microfilaments of cultured cells We have recently shown also increased phospholipase A2 activity in cells treated with toxin B The activity was detected as a toxin-induced, dose-dependent release of 14C-arachidonic acid from prelabeled
## Abstract __Clostridium difficile__βassociated disease causes diarrhea to fulminant colitis and death. We investigated the role of phospholipase A~2~ (PLA~2~) inhibitors, aristolochic acid (AA), bromophenacyl bromide (BPB) and quinacrine (QUIN) on the __C. difficile__ toxin Aβinduced disruption o