Activation of peroxisome proliferator-activated receptor γ inhibits cell growth via apoptosis and arrest of the cell cycle in human colorectal cancer
✍ Scribed by Mao Song LIN; Wei Chang CHEN; Xia BAI; Ya Dong WANG
- Book ID
- 108988713
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2007
- Tongue
- English
- Weight
- 169 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1751-2972
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## Abstract Peroxisome proliferator‐activated receptor‐gamma (PPAR‐γ) is a member of the nuclear hormone receptor superfamily of ligand‐activated transcription factors and a crucial regulator of cellular differentiation. PPAR‐γ ligands have been demonstrated to inhibit growth of several cancer cell
## Abstract ## BACKGROUND Ligand activation of peroxisome proliferator‐activated receptor γ (PPARγ) results in the inhibition of proliferation of various cancer cells. The aim of this study is to investigate the mechanisms of cell growth inhibition of hepatocellular carcinoma (HCC) cell lines by t