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Activation of p53 Tumor Suppressor by Hepatitis C Virus Core Protein

โœ Scribed by Wen Lu; Shih-yen Lo; Min Chen; Kai-jin Wu; Yuen Kai T. Fung; Jing-hsiung Ou


Book ID
112272832
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
252 KB
Volume
264
Category
Article
ISSN
0042-6822

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Tumor-suppressor p53 gene in hepatitis C
โœ Y. S. Carol Shieh; Chau Nguyen; Maria V. Vocal; Hoi-Weng Chu ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 1022 KB

Abnormalities of the tumor-suppressor p53 gene have been discovered in human hepatocellular carcinoma (HCC). It is unclear, however, whether HCC related to chronic viral hepatitis is associated with p53 gene alterations. In this study, we have examined p53 abnormalities in HCC associated with hepati