Activation of p53 transcriptional activity by 1,10-phenanthroline, a metal chelator and redox sensitive compound
β Scribed by Sun, Yi; Bian, Junhui; Wang, Yuli; Jacobs, Christine
- Book ID
- 110060494
- Publisher
- Nature Publishing Group
- Year
- 1997
- Tongue
- English
- Weight
- 634 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0950-9232
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The aminothiol WR1065, the active metabolite of the cytoprotector amifostine, exerts its antimutagenic effects through freeβradical scavenging and other unknown mechanisms. In an earlier report, we showed that WR1065 activates wildβtype p53 in MCFβ7 cells, leading to p53βdependent arres
## Abstract Myelin basic protein (MBP) is one of the major components of the myelin sheath that insulates axons. In the central nervous system, MBP is synthesized by differentiating oligodendrocytes. The expression of MBP in oligodendrocytes is regulated mainly at the transcriptional level. The Sp1