✦ LIBER ✦

Activation of p38 MAPK suppresses matrix metalloproteinase-1 gene expression induced by platelet-derived growth factor

✍ Scribed by Hideharu Endo; Atsushi Utani; Hiroshi Shinkai

Publisher: Springer-Verlag
Year: 2003
Tongue: English
Weight: 262 KB
Volume: 294
Category: Article
ISSN: 0340-3696
DOI: 10.1007/s00403-002-0364-5

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Macrophage-induced expression and releas

Macrophage-induced expression and release of matrix metalloproteinase 1 and 3 by human preadipocytes is mediated by IL-1β via activation of MAPK signaling

✍ Dan Gao; Chen Bing 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 582 KB

## Abstract Obesity is associated with a chronic low‐grade inflammation and increased macrophage infiltration in adipose tissue. Matrix metalloproteinases (MMPs) are involved in adipose tissue remodeling and inflammatory responses in obesity. This study investigated whether macrophage‐derived facto

Suppression of EGF-induced tumor cell mi

Suppression of EGF-induced tumor cell migration and matrix metalloproteinase-9 expression by capsaicin via the inhibition of EGFR-mediated FAK/Akt, PKC/Raf/ERK, p38 MAPK, and AP-1 signaling

✍ Yong Pil Hwang; Hyo Jeong Yun; Jae Ho Choi; Eun Hee Han; Hyung Gyun Kim; Gye Yon 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 395 KB

## Abstract **Scope:** Capsaicin is a cancer‐suppressing agent. The aim of our study was to determine the effect of capsaicin on tumor invasion and migration; the possible mechanisms involved in this inhibition were investigated in human fibrosarcoma cells. **Methods and results:** We employed inv

Platelet-derived growth factor-BB-induce

Platelet-derived growth factor-BB-induced hypertrophy of peritubular smooth muscle cells is mediated by activation of p38 MAP-kinase and of Rho-kinase

✍ Francesca Romano; Claudia Chiarenza; Fioretta Palombi; Antonio Filippini; Fabriz 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 438 KB

## Abstract Peritubular smooth muscle cells (PSMC) from rat testis in primary serum‐free cultures unexpectedly undergo contraction and subsequent cell hypertrophy in response to the growth factor PDGF‐BB, remaining stationary. The present study investigates the transduction pathways involved in the

Suppression of phorbol-12-myristate-13-a

Suppression of phorbol-12-myristate-13-acetate-induced tumor cell invasion by bergamottin via the inhibition of protein kinase Cδ/p38 mitogen-activated protein kinase and JNK/nuclear factor-κB-dependent matrix metalloproteinase-9 expression

✍ Yong Pil Hwang; Hyo Jeong Yun; Jae Ho Choi; Keon Wook Kang; Hye Gwang Jeong 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 490 KB

Matrix metalloproteinase (MMP) plays an important role in the invasion and metastasis of cancer cells. The inhibitory effects of bergamottin, a cytochrome P450 inhibitor from Citrus paradis (grapefruit), on tumor invasion and migration and the possible mechanisms involved in this inhibition were inv

Regulation of matrix metalloproteinase-2

Regulation of matrix metalloproteinase-2 (MMP-2) by hepatocyte growth factor/scatter factor (HGF/SF) in human glioma cells: HGF/SF enhances MMP-2 expression and activation accompanying up-regulation of membrane type-1 MMP

✍ Ryouichi Hamasuna; Hiroaki Kataoka; Takuzou Moriyama; Hiroshi Itoh; Motoharu Sei 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 French ⚖ 292 KB 👁 2 views

Hepatocyte growth factor/scatter factor (HGF/SF) contributes to the malignant progression of human gliomas. We investigated the effect of HGF/SF on matrix metalloproteinase-2 (MMP-2), membrane type 1 matrix metalloproteinase (MT1-MMP) and tissue inhibitors of metalloproteinases (TIMPs), expressions