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Activation of p38 MAPK induces cell cycle arrest via inhibition of Raf/ERK pathway during muscle differentiation

โœ Scribed by Jinhwa Lee; Feng Hong; Sijoong Kwon; Sam Soo Kim; Dong Ok Kim; Heung Sun Kang; Su Jae Lee; Joohun Ha; Sung Soo Kim

Book ID
117052842
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
322 KB
Volume
298
Category
Article
ISSN
0006-291X

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## Abstract We studied the effects of cyclosporin A (CsA) on the erythroid differentiation of human erythroid leukemia cell line K562. After K562 was treated with CsA for 4 days, the percentage of hemoglobinized cells was increased by 3.3 times. Because it was reported p38 MAPK (p38) and ERK are in