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Activation of P38 kinase links π phosphorylation, oxidative stress and cell cycle-related events in Alzheimer disease

✍ Scribed by Zhu, Xiongwei; Raina, Arun K.; Rottkamp, Catherine A.; Boux, Heather; Siedlak, Sandra L.; Takeda, Atsushi; Perry, George; Smith, Mark A.


Book ID
123017202
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
186 KB
Volume
21
Category
Article
ISSN
0197-4580

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## Abstract Two of the earliest manifestations of the selective neurodegeneration that occurs in Alzheimer's disease (AD) involve the oxidative modification of various biomacromolecules and the reexpression of a multitude of cell cycle‐related proteins. Taken together with the proximal and ectopic