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Activation of p38 Kinase in the Gerbil Hippocampus Showing Ischemic Tolerance

โœ Scribed by Nishimura, Masaki; Sugino, Toshiyuki; Nozaki, Kazuhiko; Takagi, Yasushi; Hattori, Itaro; Hayashi, Junya; Hashimoto, Nobuo; Moriguchi, Tetsuo; Nishida, Eisuke


Book ID
110088594
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
517 KB
Volume
23
Category
Article
ISSN
0271-678X

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## Abstract Excessive release of glutamate during transient cerebral ischemia initiates a cascade of events that leads to the delayed and selective death of neurons located in the hippocampus. Activity of calcium calmodulin kinase II (CaM kinase), a protein kinase critical to neuronal functioning,