Activation of P2-purino-,α1-adreno and H1-histamine receptors triggers cytoplasmic calcium signalling in cerebellar purkinje neurons

p38 mitogen-activated protein kinase and

p38 mitogen-activated protein kinase and calcium channels mediate signaling in depolarization-induced activation of peroxisome proliferator-activated receptor gamma coactivator-1α in neurons

✍ Huan Ling Liang; Shilpa S. Dhar; Margaret T.T. Wong-Riley 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 532 KB

## Abstract Peroxisome proliferator‐activated receptor gamma coactivator 1α (PGC‐1α) coactivates a number of transcription factors critical for mitochondrial biogenesis. Previously, we found that the expression of PGC‐1α is governed by neuronal activity, but the signaling mechanism is poorly unders