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Activation of NR2B-containing NMDA receptors is not required for NMDA receptor-dependent long-term depression

✍ Scribed by Wade Morishita; Wei Lu; Gordon B. Smith; Roger A. Nicoll; Mark F. Bear; Robert C. Malenka


Book ID
116784654
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
516 KB
Volume
52
Category
Article
ISSN
0028-3908

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Hippocampal synaptic metaplasticity requ
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The potential to exhibit synaptic plasticity itself is modulated by previous synaptic activity, which has been termed as metaplasticity. In this paper, we demonstrated that the activation of N-methyl-d-aspartate (NMDA) receptor 2B (NR2B) subunit in NNDA receptors was required for hippocampal metapla