Activation of NF-κB in intestinal epithelial cells byE. colistrains isolated from the colonic mucosa of IBD patients

Tumor necrosis factor-α represses the ex

Tumor necrosis factor-α represses the expression of NHE2 through NF-κB activation in intestinal epithelial cell model, C2BBe1

✍ Md. Ruhul Amin; Temitope Orenuga; Sangeeta Tyagi; Pradeep K. Dudeja; Krishnamurt 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 974 KB

Background: High levels of proinflammatory cytokines are linked to pathogenesis of diarrhea in inflammatory bowel disease (IBD). Na þ absorption is compromised in IBD. The studies were designed to determine the effect of tumor necrosis factor-a (TNFa) on the expression and activity of NHE2, a Na þ /