Activation of NF-κB by fluid shear stress, but not TNF-α, requires focal adhesion kinase in osteoblasts

NF-κB, but not p38 MAP Kinase, is requir

NF-κB, but not p38 MAP Kinase, is required for TNF-α-induced expression of cell adhesion molecules in endothelial cells

✍ Suja Rajan; Jianming Ye; Shanshan Bai; Faqing Huang; Yan-Lin Guo 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 313 KB

## Abstract In response to inflammation stimuli, tumor necrosis factor‐α (TNF‐α) induces expression of cell adhesion molecules (CAMs) in endothelial cells (ECs). Studies have suggested that the nuclear factor‐κB (NF‐κB) and the p38 MAP kinase (p38) signaling pathways play central roles in this proc