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Activation of neuronal nitric oxide synthase (nNOS) signaling pathway in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced neurotoxicity

✍ Scribed by Jiang, Junkang; Duan, Zhiqing; Nie, Xiaoke; Xi, Hanqing; Li, Aihong; Guo, Aisong; Wu, Qiyun; Jiang, Shengyang; Zhao, Jianya; Chen, Gang

Book ID
124145648
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
607 KB
Volume
38
Category
Article
ISSN
1382-6689

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## Abstract 2,3,7,8‐Tetrachlorodibenzo‐__p__‐dioxin (TCDD) is a potent immunosuppressant in several animal species. The purpose of this study was to determine if TCDD affected the activity of adenosine deaminase (ADA), a purine metabolizing enzyme that is vital to the proper functioning of the immu