𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Activation of mTOR signaling by novel fluoromethylene phosphonate analogues of phosphatidic acid

✍ Scribed by Yong Xu; Yimin Fang; Jie Chen; Glenn D. Prestwich


Book ID
108073223
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
146 KB
Volume
14
Category
Article
ISSN
0960-894X

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Inhibition of mTOR signaling by oleanoli
✍ Rongping Zhou; Zhongmin Zhang; Li Zhao; Chunhong Jia; Song Xu; Qiguang Mai; Ming πŸ“‚ Article πŸ“… 2011 πŸ› Elsevier Science 🌐 English βš– 344 KB

## Abstract Oleanolic acid (OA), a pentacyclic triterpenoid exhibits potent anti‐tumor activity against many tumor cell lines. But the mechanisms through which OA inhibits osteosarcoma cells are not known. The mammalian target of rapamycin (mTOR) serves as a central regulator of cell growth, prolif

ChemInform Abstract: Synthesis and anti-
✍ Jin Cheol Yoo; Hua Li; Wonjae Lee; Joon Hee Hong πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons βš– 37 KB πŸ‘ 2 views

## Abstract The cyclopentane moiety is synthesized from aldehyde (I) through a de novo acyclic synthetic route using reiterative Grignard additions and ring‐closure metathesis to produce the required synthon (VIII).