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Activation of mitogen-activated protein kinases by cisplatin and their role in cisplatin-resistance

✍ Scribed by Anamaria Brozovic; Maja Osmak

Book ID: 116334308
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 290 KB
Volume: 251
Category: Article
ISSN: 0304-3835
DOI: 10.1016/j.canlet.2006.10.007

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## Abstract Local control of osteoblast differentiation and bone formation is not well understood. We have previously seen biphasic effects on cell differentiation in response to the short‐ and long‐term exposure to IL‐1β in rat calvarial osteoblasts. To characterize the signaling pathway mechanism