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Activation of metabotropic glutamate receptor mediates upregulation of transcription factor mRNA expression in rat striatum induced by acute administration of amphetamine

โœ Scribed by Limin Mao; John Q Wang


Book ID
113997722
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
486 KB
Volume
924
Category
Article
ISSN
0006-8993

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Selective activation of group I metabotr
โœ Limin Mao; John Q. Wang ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 648 KB

Group I metabotropic glutamate receptors (mGluRs) are positively coupled to phosphoinositide hydrolysis through G-proteins and are densely expressed in the medium-sized spiny neurons of striatum. Activation of this group of mGluRs in the striatum produces long-lasting stimulation of behavioral activ