Activation of c-Jun NH2-terminal kinase
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Hui Liu; Yunshan Liu; Manjula Viggeswarapu; Zhaomin Zheng; Louisa Titus; Scott D
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Article
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2011
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American Society for Bone and Mineral Research
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English
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## Abstract Bone morphogenetic protein 2 (BMPโ2) plays a critical role in the differentiation of precursor cells and has been approved for clinical application to induce new bone formation. To date, unexpectedly high doses of recombinant BMPโ2 have been required to induce bone healing in humans. Th