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Activation of large-conductance potassium channels in pregnant human myometrium by pinacidil

✍ Scribed by Raheela N. Khan; John J. Morrison; Stephen K. Smith; Michael L.J. Ashford


Book ID
113985835
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
186 KB
Volume
178
Category
Article
ISSN
1097-6868

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The effect of pinacidil, an opener of ATP-sensitive K + (K ATP ) channels, on large-conductance Ca 2+ -activated K+ (BK Ca ) channels was investigated in cultured endothelial cells of human umbilical veins. In whole cell configuration, pinacidil (30 Β΅M) increased the amplitude of K + outward current