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Activation of Krox20 gene expression by Sox10 in myelinating Schwann cells

✍ Scribed by Simone Reiprich; Jana Kriesch; Silke Schreiner; Michael Wegner


Book ID
111183788
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
653 KB
Volume
112
Category
Article
ISSN
0022-3042

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Krox-20 and Krox-24 (Egr-1) encode closely related zinc finger transcription factors, which interact with the same DNA target sequences. Krox-20 is required for myelination in the peripheral nervous system. Using lacZ knock-in mutant mouse lines as well as immunohistochemical analyses, we have studi

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