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Activation of Integrin—RACK1/PKCα signalling in human articular chondrocyte mechanotransduction

✍ Scribed by H.-S. Lee; S.J. Millward-Sadler; M.O. Wright; G. Nuki; R. Al-Jamal; D.M. Salter

Book ID
114476399
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
295 KB
Volume
10
Category
Article
ISSN
1063-4584

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✍ Judit I. Pulai; Marcello Del Carlo Jr.; Richard F. Loeser 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 303 KB 👁 1 views

## Abstract ## Objective Chondrocyte cell death may play an important role in the development of arthritis. The goal of the present study was to evaluate the role of the extracellular matrix (ECM) in promoting chondrocyte survival via signals through the integrin family of ECM receptors. ## Metho