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Activation of human T cell leukemia virus type 1 LTR promoter and cellular promoter elements by T cell receptor signaling and HTLV-1 Tax expression

✍ Scribed by Hsin-Ching Lin; Michele Hickey; Lydia Hsu; Daniel Medina; Arnold B. Rabson


Book ID
113946404
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
344 KB
Volume
339
Category
Article
ISSN
0042-6822

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## Abstract Our aim was to examine the involvement of G~1~ cell‐cycle regulators in cell growth dysregulation induced by HTLV‐I. Compared to uninfected cells, higher expression levels of cyclin D1 and D2 mRNA were detected in HTLV‐I–infected T‐cell lines, which were at least in part mediated by the