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Activation of hepatic NKT cells and subsequent liver injury following administration of α-galactosylceramide

✍ Scribed by Yasser Osman; Toshihiko Kawamura; Tetsuya Naito; Kazuyoshi Takeda; Luc Van Kaer; Ko Okumura; Toru Abo


Book ID
101382345
Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
320 KB
Volume
30
Category
Article
ISSN
0014-2980

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Activation of invariant NKT cells by αGa
✍ Roberto Furlan; Alessandra Bergami; Daniela Cantarella; Elena Brambilla; Masaro 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 274 KB

## Abstract Invariant NKT (inv. NKT) cells co‐express an invariant α β T cell receptor and the NK receptor NK1.1 and, upon CD1d‐restricted recognition of the glycosphingolipid antigen α‐galactosyl ceramide (αGalCer), secrete large amounts of regulatory cytokines. We investigated whether αGalCer‐dep