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Activation of group I metabotropic glutamate receptors leads to brain-derived neurotrophic factor expression in rat C6 cells

✍ Scribed by Kittikun Viwatpinyo; Sukumal Chongthammakun


Book ID
116771786
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
497 KB
Volume
467
Category
Article
ISSN
0304-3940

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Group I metabotropic glutamate receptors (mGluRs) are positively coupled to phosphoinositide hydrolysis through G-proteins and are densely expressed in the medium-sized spiny neurons of striatum. Activation of this group of mGluRs in the striatum produces long-lasting stimulation of behavioral activ