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Activation of Glutamate Dehydrogenase by Leucine and Its Nonmetabolizable Analogue in Rat Brain Synaptosomes

✍ Scribed by Maria Erecińska; David Nelson

Book ID
111175583
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
894 KB
Volume
54
Category
Article
ISSN
0022-3042

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Activation of arginine metabolism to glutamate in rat brain synaptosomes in thioacetamide-induced hepatic encephalopathy: An adaptative response?
✍ Dr. J. Albrecht; W. Hilgier; U. Rafalowska 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 489 KB

Crude (P2) synaptosomes derived from rats with acute hepatic encephalopathy (HE) induced with thioacetamide showed a slightly increased uptake of radiolabeled arginine (ARC) and a 2.5-fold enhanced conversion of newly taken-up ARC to both glutamate (GLU) and y-aminobutyric acid (GABA) as compared wi