Tunicamycin (TM), a naturally occurring antibiotic, blocks the first step in the biosynthesis of N-linked oligosaccharides in cells. In this study, we investigated whether changes in N-linked glycosylation affect the sensitivity of head-and-neck carcinoma cell lines to cis-diaminedichloroplatinum(II
โฆ LIBER โฆ
Activation of ER stress and inhibition of EGFR N-glycosylation by tunicamycin enhances susceptibility of human non-small cell lung cancer cells to erlotinib
โ Scribed by Yi-He Ling; Tianhong Li; Roman Perez-Soler; Missak Haigentz
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 590 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0344-5704
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Inhibition of N-linked glycosylation by
โ
Ichiro Noda; Shigeharu Fujieda; Mizue Seki; Nobuyuki Tanaka; Hiroshi Sunaga; Tos
๐
Article
๐
1999
๐
John Wiley and Sons
๐
French
โ 155 KB
๐ 2 views
Expression of the major vault protein LR
โ
Walter Berger; Leonilla Elbling; Michael Micksche
๐
Article
๐
2000
๐
John Wiley and Sons
๐
French
โ 419 KB
๐ 2 views
Non-small-cell lung cancer (NSCLC) cells are characterised by resistance to the toxic impact of antineoplastic drugs both in vivo and in vitro. The lung resistance-related protein (LRP), identical with the human major vault protein, is over-expressed in a variety of tumour cells characterised by int