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Activation of endoplasmic reticulum stress response following trauma-hemorrhage

✍ Scribed by Bixi Jian; Chi-Hsun Hsieh; Jianguo Chen; Mashkoor Choudhry; Kirby Bland; Irshad Chaudry; Raghavan Raju


Book ID
116270678
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
559 KB
Volume
1782
Category
Article
ISSN
0925-4439

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Activation of endoplasmic reticulum stre
✍ Verena Christen; Susan Treves; Francois H. T. Duong; Markus H. Heim πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 431 KB

The up-regulation of protein phosphatase 2 A (PP2A) is an important factor leading to an inhibition of IFN␣ signaling caused by viral protein expression. Here, we describe the molecular mechanism involved in PP2Ac up-regulation by HCV and HBV. HCV and HBV protein expression in cells induces an ER st