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Activation of Egr-1 Expression in Astrocytes by HIV-1 Tat: New Insights into Astrocyte-Mediated Tat Neurotoxicity

✍ Scribed by Fan, Yan; Zou, Wei; Green, Linden A.; Kim, Byung Oh; He, Johnny J.


Book ID
107380749
Publisher
Springer US
Year
2010
Tongue
English
Weight
312 KB
Volume
6
Category
Article
ISSN
1557-1890

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## Abstract HIV‐1 Tat protein is an important pathogenic factor in HIV‐1‐associated neurological diseases. One hallmark of HIV‐1 infection of the central nervous system (CNS) is astrocytosis, which is characterized by elevated glial fibrillary acidic protein (GFAP) expression in astrocytes. We have