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Activation of Dendritic Cells by IL-33 Initiates a Th2 Response

✍ Scribed by Rank, M.A.; Kabayashi, T.; Bartemes, K.R.; Kita, H.

Book ID
119281365
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
39 KB
Volume
123
Category
Article
ISSN
1097-6825

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## Abstract IL‐33 is becoming a central molecule in allergic asthma that addresses various cascades of innate and adaptive immune responses that lead to inflammation in the lung. Its effects are exerted via its heterodimeric receptor that consists of ST2 and the ubiquitously expressed IL‐1 receptor