𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Activation of defence-related genes during senescence: a correlation between gene expression and cellular damage

✍ Scribed by Patricia Obregón; Raquel Martín; Ana Sanz; Carmen Castresana


Book ID
110292864
Publisher
Springer
Year
2001
Tongue
English
Weight
155 KB
Volume
46
Category
Article
ISSN
0167-4412

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Decreased expression and activity of the
✍ Muthupalaniappan Meyyappan; Keith Wheaton; Karl T. Riabowol 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 265 KB 👁 2 views

Human diploid fibroblasts (HDFs) undergo a limited number of population doublings in culture before reaching the end of their proliferative life span, an event termed in vitro cellular senescence. Considerable evidence suggests that altered expression of key genes involved in the mitogenic response

Alterations in the molecular response to
✍ Augustine M. K. Choi; Robert J. Pignolo; Colette M. J. Ap Rhys; Vincent J. Crist 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 993 KB

Transcriptional activation of c-fos in response to both serum stimulation and D N A damage requires the serum response element. The inability of in vitro aged or senescent fibroblasts to proliferate in response to serum has been shown to be associated with repressed c-fos expression and reduced AP-1

Protein kinase Cα is differentially acti
✍ Angela Di Baldassarre; Mariacristina Di Rico; Antonella Di Noia; Tiziana Bonfini 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 369 KB

## Abstract PKCα was found to be expressed (mRNA and protein) throughout the in vitro maturation of primary human erythroblasts but its activity (phosphorylation levels and nuclear localization) was consistently higher in cells derived from human neonatal rather than adult blood. Since the γ/γ + β