This study demonstrates that the engagement of CD40 results in the activation of the recently described I O B kinase (IKK) in a human B cell line. The kinase appears to reside within the cell in a cytosolic signalsome complex consisting of IKK, I O B, and an MKP-1-like molecule. While the binding of
✦ LIBER ✦
Activation of CD40 by soluble recombinant human CD40 ligand inhibits human glioma cells proliferation via nuclear factor-κB signaling pathway
✍ Scribed by Zhang, Yong; Huang, Tao; Hu, Yi; Wang, Yu
- Book ID
- 119992355
- Publisher
- Springer-Verlag
- Year
- 2012
- Tongue
- Chinese
- Weight
- 562 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0510-9752
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