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Activation of caspase-3-like protease in β-amyloid-induced apoptosis of cultured rat cortical neurons

✍ Scribed by Jun Harada; Masahiko Sugimoto

Book ID: 117365196
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 79 KB
Volume: 31
Category: Article
ISSN: 0168-0102
DOI: 10.1016/s0168-0102(98)82472-3

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## Abstract Huperzine A, a novel __Lycopodium__ alkaloid originally discovered in the Chinese herb Qian Ceng Ta (__Huperzia serrata__), is a reversible, potent, and selective acetylcholinesterase (AChE) inhibitor and has been extensively used for the treatment of Alzheimer's disease (AD) in China.