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Activation of cardiac muscarinic receptor and ischemic preconditioning effects in in situ rat heart

✍ Scribed by Fuminari Yamaguchi; Yoshihisa Nasa; Ken-ichi Yabe; Shigeru Ohba; Yoko Hashizume; Hisae Ohaku; Ken-ichi Furuhama; Satoshi Takeo


Publisher
Springer
Year
1997
Tongue
English
Weight
1002 KB
Volume
12
Category
Article
ISSN
0910-8327

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Activation of calcineurin expression in
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## Abstract Calcineurin (CaN) has been reported as a critical mediator for cardiac hypertrophy and cardiac myocyte apoptosis. In the present study, we investigated the activity and expression of CaN and the effect of calpain in rat heart after ischemia and reperfusion. Rat ischemic heart showed sig