Methylglyoxal (MG) is a physiological metabolite, but it is known to be toxic, inducing stress in cells and causing apoptosis. This study examines molecular mechanisms in the MG-induced signal transduction leading to apoptosis, focusing particularly on the role of JNK activation. We first confirmed
Activation of c-Jun N-terminal kinase is essential for oxidative stress-induced Jurkat cell apoptosis by monochloramine
β Scribed by Tetsuya Ogino; Michitaka Ozaki; Mutsumi Hosako; Masako Omori; Shigeru Okada; Akihiro Matsukawa
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 787 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0145-2126
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