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Activation of autologous leukemia-specific T cells in acute myeloid leukemia: monocyte-derived dendritic cells cocultured with leukemic blasts compared with leukemia-derived dendritic cells

✍ Scribed by Andreas Draube; Marc Beyer; Jürgen Wolf


Book ID
114794439
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
256 KB
Volume
81
Category
Article
ISSN
0902-4441

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Although a second stem cell transplantation (SCT) can be used as salvage therapy in patients with relapsing leukemia after SCT, most of these patients have a poor outcome. We tried clinical vaccination using monocyte-derived dendritic cells (DCs) pulsed with leukemic lysates to treat relapsing acute