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Activation of ATP-sensitive potassium channels in follicle-enclosedXenopusoocytes by the epileptogenic agent pentylenetetrazol

✍ Scribed by N. Klöcker, U. Mußhoff, M. Madeja, E. -J. Speckmann


Book ID
120903814
Publisher
Springer
Year
1996
Tongue
English
Weight
226 KB
Volume
431
Category
Article
ISSN
0031-6768

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Modulation of ATP-sensitive potassium ch
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We have used 'caged-ATP' to investigate the kinetic behavior of KATP channels in ventricular cells from rat heart. In whole cells, loaded with 'caged-ATP', an increase of intracellular [ATP] following a UV light flash produced a decrease of KATP channel current that was too slow (tau approximately 3