Activation of a Qa/Tla class I major histocompatibility antigen gene is a general feature of oncogenesis in the mouse
β Scribed by Brickell, Paul M.; Latchman, David S.; Murphy, David; Willison, Keith; Rigby, Peter W. J.
- Book ID
- 109733057
- Publisher
- Nature Publishing Group
- Year
- 1983
- Tongue
- English
- Weight
- 643 KB
- Volume
- 306
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/306756a0
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## Background: Recent studies have demonstrated an association of a polymorphic (gct)n triplet repeat in the transmembrane (tm) region of the major histocompatibility complex (mhc) class i chain-related gene a (mica), one of the mhc class i chain-related (mic) family members, with some autoimmune d
## Abstract Surface expression of the majority of class I major histocompatibility complex (MHC) heavy chains is known to require assembly with Ξ²~2~ microglobulin (Ξ²~2~m). To define other factors involved in class I MHC assembly, we have studied two tumor cell lines that are deficient in cell surfa