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Activation of a Drosophila heat shock transcription factor by HO in vivo and in vitro

✍ Scribed by BESTBELPOMME, M; BECKER, J; MEZGER, V; COURGEON, A


Book ID
122138230
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
136 KB
Volume
14
Category
Article
ISSN
0309-1651

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Molecular mechanisms which underlie the heat shock response have commonly been analyzed using tissue culture systems, with less investigation of the intact mammal. In tissue culture, a temperature elevation of 5Β°C is required to activate mammalian heat shock transcription factor 1 (HSF1) to the DNA-